Challenges in evaluating SARS-CoV-2 vaccines

With more than 140 SARS-CoV-2 vaccines in development, the race is on for a successful candidate to help prevent COVID-19. An effective and safe vaccine would be a major advance in the fight against COVID-19. However, there are challenges in evaluating the efficacy of these vaccines during the pandemic, as an analysis article outlines in CMAJ (Canadian Medical Association Journal). […]

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Researchers pilot 'model to data' approach to developing predictive algorithms

Patient privacy concerns can make it challenging to develop predictive models using data from electronic health records. But a new study published this week in the Journal of the American Medical Informatics Association suggests that researchers can use the “model to data” approach to develop models without having direct access to patient data. “The focus of the MTD framework is to […]

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Aerosols are a bigger coronavirus threat than WHO guidelines suggest – here’s what you need to know

When someone coughs, talks or even breathes, they send tiny respiratory droplets into the surrounding air. The smallest of these droplets can float for hours, and there is strong evidence that they can carry live coronavirus if the person is infected. The risk from these aerosols isn’t currently incorporated into the World Health Organization’s formal guidance for nations, though. The […]

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During COVID-19, women are opting for ‘freebirthing’ if homebirths aren’t available, and that’s a worry

The pandemic is prompting some Australian pregnant women to give birth at home without a midwife or registered health provider, according to a survey out this week. Another new survey helps explain why. The number of women who say they have either had or were thinking about “freebirthing” is concerning, due to the increased risk to mothers and babies when […]

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Is it safe to visit the dentist during the pandemic?

Is it safe to visit the dentist during the COVID-19 pandemic? Dentists can’t eliminate all risk, but they are taking steps to minimize the chances of spreading the coronavirus. You’ll likely notice changes as soon as you enter the office. Many dentists have removed magazines from waiting rooms, for example, as well as some chairs to encourage social distancing. They […]

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Here’s how lung, immune system in kids protect from severe Covid-19

Differences in lung physiology and immune function in children may explain why they are more often spared from severe illness associated with COVID-19 than adults, according to a research which sheds more light on the biological process behind the deadly infectious disease. Scientists, including those from The University of Texas Health Science Center at Houston (UTHealth) in the US, said […]

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Study finds decreased rates of high-cost care after a community development initiative

More than a decade into the community development initiative called Healthy Neighborhoods Healthy Families, the 30-block Southern Orchards neighborhood on Columbus, Ohio’s South Side had clear, notable improvement. Home vacancy fell from 30% to under 6%. High school graduation rates increased. More than $40 million in investments were generated in the area. But Nationwide Children’s Hospital, a lead partner in […]

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A helping hand for cancer immunotherapy

Scientists at Sanford Burnham Prebys Medical Discovery Institute have demonstrated the therapeutic potential of PRMT5 inhibitors to sensitize unresponsive melanoma to immune checkpoint therapy. PRMT5 inhibitors are currently in clinical trials in oncology, and this research provides a strong rationale for evaluating the drugs in tumors that are not responsive to immune checkpoint therapy. The study was published in Science […]

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When you take birth control every day, this is what happens to your body

Birth control comes in many forms, including what is commonly referred to as “the pill.” However, not all birth control pills are created equal.   Combination birth control pills contain both estrogen and progestin — hormones that aid in regulating a woman’s menstrual cycle (via Drugs.com). They can either be monophasic, meaning they have the same amount of each hormone, or […]

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