Has COVID-19 changed the future of pharmaceutical regulation?

Has COVID-19 revolutionized the future of regulation of medicine development and authorization or are we simply responding to an unprecedented global pandemic? Our Head of Regulatory Affairs and Enhanced Services, Harriet Edwards, delves deep on how the pandemic changed the industry we work in today. Image Credit: Albumedix Ltd. COVID-19, or SARS-CoV-2, has undoubtedly changed the world as we know […]

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Using the power of machine learning to develop a predictive model of rumination

Our minds often get trapped in repetitive thoughts, such as past mistakes, regrets, insecurities, or unresolved conflicts. This pattern of persistent negative thinking, called rumination, can have detrimental effects on mental health, leading to conditions like depression and anxiety. Recognizing rumination as a major risk factor for depression, researchers have been working to identify its neural signature and develop early […]

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Rituximab Inferior to Ocrelizumab for MS Relapse

TOPLINE: Because MS patients who take rituximab have more relapses than those who take ocrelizumab, these two therapies may not be interchangeable in clinical practice. METHODOLOGY: Ocrelizumab was the first licensed B-cell therapy for the treatment of relapsing-remitting multiple sclerosis (RRMS), while rituximab, another monoclonal antibody, is often used as an off-label alternative at a lower cost. Using data from […]

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Idina Menzel Implores Parents to ‘Keep Fighting’ Censorship & Hate Against LGBTQ+ Kids

If you purchase an independently reviewed product or service through a link on our website, SheKnows may receive an affiliate commission. As an ally for the LGBTQ+ community and a mom of a mixed-race son Walker, 13, Idina Menzel has a message for parents everywhere: “keep fighting.” The Frozen star gave a heartfelt interview about the rise in censorship and […]

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The connection between energy insecurity and poor health

In light of climate change and the impending transition to clean energy, many long-standing programs to address energy insecurity need to be refreshed. A new paper published online in the journal Health Affairs provides growing documentation of the connections between energy insecurity and poor health. The paper, by Diana Hernandez, PhD, associate professor of sociomedical sciences at Columbia University Mailman […]

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New Clues to an Old Mystery: Recent Gains in Endometriosis

In 1927, American gynecologist John Sampson published his theory of the etiology of endometriosis, postulating that retrograde flow of endometrial debris flows backward through the fallopian tubes during menses into the peritoneal cavity. Sampson’s notion remains the main paradigm today, mentioned still in recent articles on the topic, but it has a flaw: Although the theory may account for how […]

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Decreased thalamic activity is a correlate for being asleep: Study investigates neural mechanisms of anesthetics

In a study conducted at the University of Turku, Finland, the neural mechanisms of different anesthetics were investigated using functional brain imaging. Disconnection from external world and events (“sleeping”) was specifically related to reduced activity in the central thalamic nuclei in subjects who received propofol, dexmedetomidine or sevoflurane, but not in subjects who received S-ketamine. The neural mechanisms of general […]

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