How do SSRIs Interact with Monoamine Transporters?

Selective serotonin reuptake inhibitors (SSRIs) block the reuptake of serotonin by the serotonin transporter (SERT) protein, a type of monomine transporter. They are commonly used in the treatment of depression and anxiety. nobeastsofierce | Shutterstock In the nervous system, electrical signals are sent down a nerve cell (neuron) to a synapse that transmit the electrical signal from one nerve cell […]

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Clofen

NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. CLOFEN baclofen CONSUMER MEDICINE INFORMATION What is in this leaflet This leaflet answers some common questions about CLOFEN. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor […]

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Paper-based Analytical Devices Overview

The formation of microfluidic assays on paper provides the potential for portable medical tests that can be used anywhere in the world.  Credit: Chamaiporn Naprom/Shutterstock.com Paper is a hydrophilic material meaning that its affinity with water allows solutions to flow through the porous structure. This simple capillary action does not require added mechanical constructions for pumping. Bioassays can now detect […]

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What is Infrared Microscopy?

Infrared (IR) microscopy, also known as infrared microspectroscopy, is a type of light microscopy that uses a source that transmits infrared wavelengths of light to view an image of the sample. Unlike other optical microscopes with absorbent glass optics, an infrared microscope has reflective optics to allow the microscope to cover the entire spectral range of infrared light. Configuration An […]

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Affinity Chromatography – How Does it Work?

Affinity chromatography is a separation process used to purify molecules or a group of molecules that are in a biochemical mixture. It employs two phases; a stationary phase and a mobile phase. Specific molecules from the moving phase will bond to the stationary phase based on their properties whilst the rest of the solution passing through unaffected. The process is […]

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Duodopa

NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. DUODOPA®   Consumer Medicine Information (CMI) summary The full CMI on the next page has more details. If you are worried about using this medicine, speak to your doctor or pharmacist. Why am I using Duodopa? Duodopa contains the active ingredients levodopa and carbidopa.Duodopa is used to […]

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Life Science Applications of the Bottom-Up Approach

Bottom-up approach to modelling and simulation in the life sciences Human tissue-specific modelling by detailing and recreating functional components of whole tissue. The smaller subunits of biological processes that make up the whole can form a simulation of a tissue and organ under various conditions through mathematical reconstruction alone. HepatoNet1, a reconstruction of the liver is an example of the […]

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Amino Acid Metabolism

Amino acid metabolism is an important process that occurs within the human body to assist in numerous biological reactions. This article will cover the role of glutamate, transamination reactions, and various types of amino acids such as glycogenic, ketogenic, and mixed amino acids. Glutamate and Transamination Reactions The four most common amino acids in the human body are glutamate, aspartate, […]

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APO-Quinapril

NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. APO-QUINAPRIL Quinapril hydrochloride Consumer Medicine Information What is in this leaflet This leaflet answers some common questions about quinapril. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your […]

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Predicting Protein Function from DNA Sequences

Identifying the function of a protein from its sequence alone is possible using a genetics-based approach. The principle of this approach is coarse; it involves detecting the presence of mRNA encoding a protein of unknown function. ibreakstock | Shutterstock The temporal expression of RNA The expression pattern of a single gene or multiple genes can be investigated using a technique […]

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